Welcome to My Site

 
 

Education:


BS, Computer Science, Huazhong University of Science and Technology, China, 1982

PhD, Computational & Applied Mathematics, Rice University, USA, 1991


Work Experience:


Postdoc Associate, Center for Applied Mathematics, Cornell University, USA, 1991-1994

Postdoc Associate, MCS Division, Argonne National Lab, USA, 1994-1997


Staff Member, Benchmark Group, Tera Computer Company, 1997-1998

Senior Scientist, Keck Center for Computational Biology, Rice University, 1998-2000


Associate Professor, Department of Mathematics, Iowa State University, 2000-2008

Full Professor, Department of Mathematics, Iowa State University, 2008-present


Research:


Numerical optimization, numerical linear algebra, evolutionary game theory, mathematical and computational biology: protein modeling and simulation, modeling of evolution and natural selection


Selected Publications:


Evolutionary Games:


Min Wang, Wen Zhou, and Zhijun Wu, Equilibrium distributions of populations of biological species on networks of social sites, Journal of Biological Dynamics, Online on August 6, 2018


Yiping Hao and Zhijun Wu, Computation of sparse and dense equilibrium strategies of evolutionary games, Games 9, 46-60, 2018


Min Wang, Yuanyuan Huang, and Zhijun Wu, Simulation of yeast cooperation in 2D, Bulletin of Mathematical Biology 78, 531-555, 2016


Yuanyuan Huang, Min Wang, Yiping Hao, Wen Zhou, and Zhijun Wu, Optimality and stability conditions of symmetric evolutionary games with applications in genetic selection, Journal of Mathematical Biosciences and Engineering 12, 503-523, 2015


Yuanyuan Huang and Zhijun Wu, Game dynamic model for yeast development, Bulletin of Mathematical Biology 74, 1469-1484, 2012


Protein Dynamics:


Junkoo Park, Robert Jernigan, and Zhijun Wu, Coarse-grained NMA vs. refined GNM for protein residue-level fluctuations, Bulletin of Mathematical Biology 75, 124-160, 2013


Peter Vedell and Zhijun Wu, A multiple shooting algorithm for solving the boundary value problems in molecular dynamics simulation, Numerical Analysis and Modeling 10, 920-942, 2013


Ajith Gunaratne and Zhijun Wu, A penalty-function method for constrained molecular dynamics simulation, Numerical Analysis and Modeling 8, 496-517, 2011


Di Wu, Steve Smith, Hanna Mahan, Robert Jernigan, and Zhijun Wu, Analysis of protein dynamics using local DME calculations, International Journal of Bioinformatics Research and Applications 7, 146-161, 2011


Di Wu and Zhijun Wu, Superimposition of protein structures with dynamically weighted RMSD, Journal of Molecular Modeling 16, 611-622, 2010


Structural Bioinformatics:


Yuanyuan Huang, Kejue Jia, Robert Jernigan, and Zhijun Wu, A Web server for protein structure evaluation using residue level angle correlation plots, in Proceedings of 2015 International Symposium on Bioinformatics Research and Applications, Springer, 2015


Yuanyuan Huang, Stephen Bonett, Andrzej Kloczkowski, Robert Jernigan, and Zhijun Wu, Statistical measures on protein residue level structural properties, Journal of Structural and Functional Genomics 12, 119-136, 2011


Feng Cui, Kriti Mukhopadhyay, Wonbin Young, Robert Jernigan, and Zhijun Wu, Improvement of under-determined loop regions of human prion protein by database derived distance constraints, International Journal of Data Mining and Bioinformatics 3, 454-468, 2009


Di Wu, Robert Jernigan, and Zhijun Wu, Refinement of NMR-determined protein structures with database derived mean force potentials, Proteins: Structure, Function, Bioinformatics 68, 232-242, 2007


Di Wu, Feng Cui, Robert Jernigan, and Zhijun Wu, PIDD: A protein inter-atomic distance distribution database, Journal of Nucleic Acid Research 35, D202-D207, 2007


Feng Cui, Robert Jernigan, and Zhijun Wu, Refinement of NMR-determined protein structures with database derived distance constraints, Journal of Bioinformatics and Computational Biology 3, 1315-1330, 2005


Molecular Distance Geometry:


Zach Voller and Zhijun Wu, Distance geometry methods for protein NMR structure determination, in Distance Geometry: Theory, Methods, and Applications, A. Mucherino, C. Lavor, L. Liberti, N. Maculan, Eds., Springer, 2012


Atilla Sit and Zhijun Wu, Solving a generalized distance geometry problem for protein structure determination, Bulletin of Mathematical Biology 73, 2809-2836, 2011


Atilla Sit, Zhijun Wu, and Yaxiang Yuan, A geometric buildup algorithm for the solution of the distance geometry problems with the least-squares approximation, Bulletin of Mathematical Biology 71, 1914-1933, 2009


Di Wu, Zhijun Wu, and Yaxiang Yuan, Rigid vs unique determination of protein structures with geometric buildup, Optimization Letters 2, 319-331, 2008


Di Wu and Zhijun Wu, An updated geometric buildup algorithm for solving the molecular distance geometry problem with sparse distance data, Journal of Global Optimization 37, 661-673, 2007

 

Zhijun Wu, Professor

Department of Mathematics

Iowa State University